N-[(9H-芴-9-基甲氧基)羰基]-L-丝氨酸水合物
Fmoc-L-Serine
CAS: 73724-45-5
Molecular Formula: C18H17NO5
N-[(9H-芴-9-基甲氧基)羰基]-L-丝氨酸水合物 - Names and Identifiers
| Name | Fmoc-L-Serine |
| Synonyms | Fmoc-Ser-OH FMoc-Ser.H2O Fmoc-L-Serine Fmoc-L-Ser-OH N-Fmoc-L-serine L-Serine-d3-N-FMOC N-Fmoc-L-serineFmoc-Ser-OH L-SERINE-N-FMOC (13C3,15N) N-Fmoc-L-serine monohydrate FMoc-Ser-OH (FMoc-L-Serine) N-(9-Fluorenylmethoxycarbonyl)-L-serine N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-serine (2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-3-hydroxypropanoate (S)-2-(((9H-fluoren-9-yl)Methoxy)carbonylaMino)-3-hydroxypropanoic acid |
| CAS | 73724-45-5 |
| EINECS | 690-938-2 |
| InChI | InChI=1/C18H17NO5/c20-9-16(17(21)22)19-18(23)24-10-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15/h1-8,15-16,20H,9-10H2,(H,19,23)(H,21,22)/p-1/t16-/m0/s1 |
N-[(9H-芴-9-基甲氧基)羰基]-L-丝氨酸水合物 - Physico-chemical Properties
| Molecular Formula | C18H17NO5 |
| Molar Mass | 327.33 |
| Density | 1.362±0.06 g/cm3(Predicted) |
| Melting Point | 104-106°C |
| Boling Point | 599.3±50.0 °C(Predicted) |
| Specific Rotation(α) | -12.5 º (c=1%, DMF) |
| Flash Point | 316.2°C |
| Solubility | soluble in Methanol |
| Vapor Presure | 3.27E-15mmHg at 25°C |
| Appearance | Powder |
| Color | White to Light yellow |
| BRN | 4715791 |
| pKa | 3.51±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | -12.5 ° (C=1, DMF) |
| MDL | MFCD00051928 |
| Use | Used for biochemical reagents, peptide synthesis. |
N-[(9H-芴-9-基甲氧基)羰基]-L-丝氨酸水合物 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| HS Code | 29242990 |
N-[(9H-芴-9-基甲氧基)羰基]-L-丝氨酸水合物 - Introduction
N-Fmoc-L-Serine (Fmoc-L-Serine) is an organic compound commonly used in peptide synthesis. The following is a description of the properties, uses, preparation and safety information of N-Fmoc-L-serine:
Nature:
-Appearance: A white to off-white granular or crystalline powder.
-Molecular formula: C21H21NO5
-Molecular weight: 371.40g/mol
-Melting point: about 100-110 degrees Celsius
Use:
- Fmoc-L-serine is a commonly used serine derivative, which can be used in solid phase synthesis or liquid phase synthesis in the field of peptide synthesis.
-It can be used as a protecting group for serine residues to protect the hydroxyl group of serine to prevent unwanted reactions.
-In the synthesis of polypeptides and proteins, Fmoc-L-serine can be used to construct complex peptide chain structures, including modification and regulation of activity.
Preparation Method:
-The preparation of Fmoc-L-serine can be obtained by synthetic chemical methods. In general, L-serine is first reacted with Fmoc-Cl(Fmoc chloride) to form N-Fmoc-L-serine under basic conditions.
Safety Information:
- Fmoc-L-Serine is a chemical and should be handled in accordance with laboratory safety procedures.
-Avoid direct contact with skin and eyes during operation to avoid irritation.
-When storing, keep Fmoc-L-serine in a dry, cool place, away from fire and oxidizing agents.
Nature:
-Appearance: A white to off-white granular or crystalline powder.
-Molecular formula: C21H21NO5
-Molecular weight: 371.40g/mol
-Melting point: about 100-110 degrees Celsius
Use:
- Fmoc-L-serine is a commonly used serine derivative, which can be used in solid phase synthesis or liquid phase synthesis in the field of peptide synthesis.
-It can be used as a protecting group for serine residues to protect the hydroxyl group of serine to prevent unwanted reactions.
-In the synthesis of polypeptides and proteins, Fmoc-L-serine can be used to construct complex peptide chain structures, including modification and regulation of activity.
Preparation Method:
-The preparation of Fmoc-L-serine can be obtained by synthetic chemical methods. In general, L-serine is first reacted with Fmoc-Cl(Fmoc chloride) to form N-Fmoc-L-serine under basic conditions.
Safety Information:
- Fmoc-L-Serine is a chemical and should be handled in accordance with laboratory safety procedures.
-Avoid direct contact with skin and eyes during operation to avoid irritation.
-When storing, keep Fmoc-L-serine in a dry, cool place, away from fire and oxidizing agents.
Last Update：2024-04-10 22:29:15
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View History
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